Which treatment is typically not recommended for toxic epidermal necrolysis?

Toxic epidermal necrolysis (TEN) is a severe dermatological condition characterized by widespread peeling of the skin and mucous membranes, often triggered by medication use. The management of TEN primarily focuses on supportive care, as the condition can lead to significant morbidity and mortality.

Supportive care is essential and includes fluid resuscitation, electrolyte management, wound care, and prevention of secondary infections. While intravenous immunoglobulin and topical antibiotics may be employed in certain cases to mitigate symptoms and provide additional support, systemic corticosteroids are not typically recommended.

The use of systemic corticosteroids in TEN can potentially worsen the condition due to their immunosuppressive effects, which may hinder the healing process and increase the risk of infections. This highlights the importance of avoiding treatments that could compromise the patient's immune response and worsen outcomes in such a vulnerable state.

In summary, while supportive care is the cornerstone of treatment for TEN, systemic corticosteroids are discouraged due to their potential adverse effects on the patient's recovery and health.