Which medication is commonly used for the treatment of hyperuricemia in patients with TEN?

Allopurinol is commonly used for the treatment of hyperuricemia, especially in patients who may have conditions like tumor lysis syndrome or severe hyperuricemia secondary to certain medications or chemotherapy. In the context of toxic epidermal necrolysis (TEN), where patients may experience significant cellular turnover, there is a risk of developing hyperuricemia due to breakdown of purines. Allopurinol works by inhibiting xanthine oxidase, which decreases the production of uric acid, thereby helping to manage elevated uric acid levels that can lead to complications such as acute kidney injury.

The other medications listed do not directly address the management of hyperuricemia associated with TEN. Lamotrigine is an anticonvulsant and mood stabilizer, phenytoin is an antiepileptic medication, and sulfasalazine is used primarily to treat inflammatory bowel disease and rheumatoid arthritis, but none of these are effective for reducing uric acid levels in a hyperuricemic context. Therefore, allopurinol is the appropriate choice for managing hyperuricemia in this scenario.