Which class of antibiotics is considered safe to use during pregnancy?

Macrolides are considered safe to use during pregnancy primarily due to their established safety profile and lower risk of adverse effects on both the mother and fetus. This class of antibiotics, which includes medications such as azithromycin and erythromycin, has been extensively studied and used in pregnant populations.

In particular, macrolides are often prescribed for respiratory infections, sexually transmitted infections, and various bacterial infections during pregnancy when necessary. They do not have teratogenic effects and are deemed appropriate for treating conditions that may arise during this sensitive period.

In contrast, other classes of antibiotics, such as tetracyclines, are associated with potential risks like tooth discoloration and negative impacts on fetal bone development. Fluoroquinolones may carry risks related to cartilage damage and are generally avoided unless no alternatives are available. Glycopeptides are typically used in specific scenarios, such as serious infections caused by resistant organisms, but their safety profile during pregnancy is not as well established as that of macrolides. Therefore, the preference for macrolides in pregnant patients is well supported by clinical guidelines and research data.