What was noted about the effects of steroids in treating Stevens-Johnson syndrome?

In the context of treating Stevens-Johnson syndrome (SJS), it is understood that the use of systemic corticosteroids is not effective in altering the course of the disease. While steroids are known to have anti-inflammatory properties, the evidence does not support their general use in managing SJS due to concerns about potential adverse effects and lack of demonstrable benefits in severe cutaneous adverse reactions. Therefore, the statement that they do not help aligns with the current understanding that steroids neither modify the disease process nor lead to better outcomes when used in this particular condition.

This is an important point in managing patients with SJS, as treatment focuses primarily on supportive care, including fluid management, pain control, and wound care. Other therapies, such as immunoglobulins or targeted treatments in specific cases, may be considered, but systemic corticosteroids have not shown substantial efficacy.