What is a common treatment option for primary and secondary syphilis?

The most common treatment option for both primary and secondary syphilis is a single intramuscular (IM) injection of penicillin. This is due to penicillin's effectiveness against Treponema pallidum, the bacterium responsible for syphilis. Penicillin has been the cornerstone of treatment since the discovery of antibiotics, and it remains the gold standard due to its high efficacy and safety profile.

In cases of primary syphilis, which may present with a painless ulcer known as a chancre, and secondary syphilis, characterized by systemic symptoms and skin rashes, penicillin is the treatment of choice. The single-dose IM administration provides adequate serum levels to effectively eradicate the infection.

Other treatment options might be explored in patients with penicillin allergies or those who cannot receive it; however, penicillin remains the definitive treatment for uncomplicated syphilis.