What is a common neurological manifestation of vitamin B12 deficiency?

A common neurological manifestation of vitamin B12 deficiency is peripheral neuropathy. This condition arises from a lack of vitamin B12, which plays a crucial role in the synthesis of myelin, the protective sheath surrounding nerves. When this synthesis is disrupted, nerves can become damaged, leading to symptoms such as numbness, tingling, and weakness, particularly in the hands and feet.

Additionally, vitamin B12 deficiency can lead to other neurological issues, such as ataxia, which involves a loss of coordination and balance due to cerebellar dysfunction. However, peripheral neuropathy is more directly linked to the deficiency itself and is frequently one of the first symptoms to appear, making it a common and significant manifestation.

Seizures and visual disturbances can occur in various neurological conditions but are not specifically associated with vitamin B12 deficiency. Thus, while ataxia is a manifestation, peripheral neuropathy is more frequently recognized as a direct consequence of vitamin B12 deficiency and serves as a primary indicator in clinical practice.