Hand-foot-mouth disease is predominantly caused by which virus?

Hand-foot-mouth disease is predominantly caused by viruses from the enterovirus family, with Coxsackievirus being one of the most common specific causative agents. This viral infection primarily affects children and is characterized by fever, sores in the mouth, and a rash on the hands and feet.

Coxsackieviruses, particularly Coxsackievirus A16 and enterovirus 71, are frequently implicated in outbreaks of hand-foot-mouth disease. The communicable nature of these viruses, along with their stability in the environment, aids in the spread among children, especially in settings like daycare centers.

Other viruses listed, such as rhinoviruses and herpes simplex viruses, do not have the same association with hand-foot-mouth disease. Rhinoviruses are primarily responsible for the common cold, while herpes simplex viruses are known for causing oral and genital herpes but are not linked to this particular disease. Thus, understanding the primary role of Coxsackievirus in hand-foot-mouth disease provides insight into its pathogenesis and helps direct appropriate public health measures in instances of outbreaks.